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“FcgammaRIIA ligation in RS4;11 and 380 cells induced tyrosine phosphorylation of CD32, CD19, CBL , SYK, P13-K p85 and SHIP, as well as RasGAP association with tyrosine-phosphorylated p62(dok).”
Bioscience, biotechnology, and biochemistry • 2000 | View Paper
“Initially, it causes an increase in the association between scFv-Syk and the cytosolic protein Cbl and subsequently promotes tyrosine phosphorylation of Cbl.”