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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Chloral Hydrate
supplement:
Choline
Research Papers that Mention the Interaction
“ Chloral hydrate had a biphasic effect on choline , consisting of a shortlasting (20 min) initial decrease followed by an increase.”
The effects of anaesthesia and hypothermia on interstitial concentrations of acetylcholine and choline in rat striatum.“Administration of pentobarbital (65 mg/kg), chloral hydrate (40 mg/kg) and γbutyrelactone (750 mg/kg) caused a 50‐80% reduction in sodium‐dependent high affinity choline uptake in several brain regions (30 min).”
“Administration of pentobarbital, chloral hydrate , morphine, physostigmine, Δ9 THC, hemicholinium-3 and oxotremorine, drugs which decrease ACh turnover and release, caused a reduction in choline uptake.”
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