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“Comparison of the PEG method with a published method using dextran-coated charcoal and the natural hormone showed differences that may perhaps be explained by variable dissociation of progesterone from nonspecific and possibly specific binding components in the presence of charcoal.”
Journal of steroid biochemistry • 1980 | View Paper
“ Charcoal extraction , but not heat treatment, significantly removed the inhibitory effect of the conditioned media on progesterone production by oocytectomized COC.”