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Last Updated: 5 months ago

Possible Interaction: Charcoal and Ipecac

supplement:

Ipecac

Research Papers that Mention the Interaction

A complication rate of 5.4% was found with the ipecac and activated charcoal treatment compared with a 0.9% complication rate in the activated charcoal group (P less than or equal to .05).
Annals of emergency medicine  •  1989  |  View Paper
A study was conducted in ten human volunteers to determine if activated charcoal prevents the emetic effect of syrup of ipecac when a temporal separation exists between administration of the two substances.
Activated charcoal is reported to block the emetic effect of syrup of ipecac.
Preservation of the emetic effect of syrup of ipecac in the presence of activated charcoal may produce a synergistic effect by enhancing toxin elimination.
Journal of toxicology. Clinical toxicology  •  1986  |  View Paper
Because the use of ipecac allowed an absorption of the drugs at least 30 fold that allowed by charcoal , the immediate administration of activated charcoal, without preceding lavage or emesis, should be considered in such poisonings where the adsorption capacity of high charcoal doses will not be saturated.
Journal of toxicology. Clinical toxicology  •  1984  |  View Paper
Ipecac may delay the administration or reduce the effectiveness of activated charcoal , oral antidotes, and whole bowel irrigation.
Clinical toxicology  •  2013  |  View Paper
Equally importantly administration of syrup of ipecac may delay administration or reduce effectiveness of activated charcoal , the gastric decontamination agent of choice.
Clinical medicine  •  2011  |  View Paper
Ipecac may delay the administration or reduce the effectiveness of activated charcoal , oral antidotes, and whole bowel irrigation.
Journal of toxicology. Clinical toxicology  •  2004  |  View Paper
Ipecac may delay the administration or reduce the effectiveness of activated charcoal , oral antidotes, and whole bowel irrigation.
Journal of toxicology. Clinical toxicology  •  1997  |  View Paper