“Concomitant administration of MgCl2 significantly attenuated the enhancing effect of caerulein on gastric carcinogenesis.”
“Rats treated with caerulein had a significantly elevated labeling index of the antral mucosa which was significantly decreased by concomitant administration of MgCl2 and/or of verapamil, as compared with the labeling index observed after treatment with caerulein alone.”
“These findings indicate that caerulein enhances gastric carcinogenesis and that MgCl2 and verapamil attenuate this enhancement.”