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“When dispersed acinar cells pre‐… with [14C]5‐HT and [3H]leucine are … with caerulein , there is a synchronous increase in amylase activity and secretion of [14C]5‐HT and [3H]protein; … ratios of [3H]protein/[14C]5‐HT in zymogen granules and in the secretory products are identical.”
“Carbamylcholine (> 1 · 10 −6 M), pancreozymin (> 0.1 unit/ml) or caerulein (> 2 ng/ml) inhibit the incorporation of L [4,5- 3 H 2 ] leucine intoacid-insoluble proteins of the rat pancreas in vitro .”
“By contrast, a two‐fold increase in the incorporation of leucine was found in fasting animals injected subcutaneously with caerulein twice a day for 4 days.”