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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Cerulenin and Fatty Acids, Monounsaturated

Research Papers that Mention the Interaction

The addition of cerulenin to the medium increased the proportion of DHA and saturated fatty acids, including C12:0, C14:0 and C16:0, at the expense of monounsaturated fatty acids , including C16:1 and C18:1.
PloS one  •  2016  |  View Paper
Treatment of cells with cerulenin resulted in significantly reduced level of C16 monounsaturated fatty acid (C16:1Δ9t, C16:1Δ7).
Microbial Cell Factories  •  2016  |  View Paper
The biosynthesis of monounsaturated fatty acids was significantly inhibited (10-37%) by the addition of cerulenin , whereas the concentrations of PUFAs increased by 2-4 times.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology  •  2004  |  View Paper
Treatment of cells with cerulenin inhibited MUFA but not PUFA synthesis and led to a decreased growth rate and yield at low temperature and high pressure.
Applied and Environmental Microbiology  •  1999  |  View Paper
Monounsaturated and polyunsaturated C18 fatty acids were most effective in relieving growth inhibition mediated by cerulenin.
Journal of bacteriology  •  1983  |  View Paper