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“The addition of cerulenin to the medium increased the proportion of DHA and saturated fatty acids, including C12:0, C14:0 and C16:0, at the expense of monounsaturated fatty acids , including C16:1 and C18:1.”
“The biosynthesis of monounsaturated fatty acids was significantly inhibited (10-37%) by the addition of cerulenin , whereas the concentrations of PUFAs increased by 2-4 times.”
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology • 2004 | View Paper
“Treatment of cells with cerulenin inhibited MUFA but not PUFA synthesis and led to a decreased growth rate and yield at low temperature and high pressure.”