“Glutamate accumulation and glutamine synthesis were found to be inhibited by cephaloridine after 90 and 180 min of incubation, and cephaloridine accumulation in the renal proximal cells occurred in a time-dependent manner.”
“In an attempt to improve our knowledge in this field, we have studied the influence of cephaloridine on the synthesis of glutamine , which represents a key metabolic process involving several important enzymatic steps in the rabbit kidney.”