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Last Updated: 2 years ago

Possible Interaction: Central Nervous System Stimulants and Progesterone

Research Papers that Mention the Interaction

Depending on the cell and tissue, the hormonal environment, growth conditions and the developmental stage, progesterone can either stimulate cell growth or inhibit it while promoting differentiation.
The Journal of Steroid Biochemistry and Molecular Biology  •  2014  |  View Paper
Ethynyl estradiol and progesterone were able to significantly stimulate P-gp ATPase activity in a concentration-dependent manner.
Pharmaceutical Research  •  2004  |  View Paper
Progesterone inhibits cell proliferation, stimulates differentiation of endometrial cells, and is also important for maintenance of pregnancy, while 5alpha-THP allosterically modulates the activity of the gamma-aminobutyric acid receptor.
Chemico-biological interactions  •  2009  |  View Paper
In summary, there is converging evidence from studies in humans that (a) men and women do differ in their subjective response to …; (b) these sex differences are evident when women are in the luteal phase, when progesterone levels are elevated; and (c) progesterone administration attenuates the … response to stimulants.
Rather, the hormone progesterone has been shown to attenuate the subjective response to stimulants , particularly in women.
Recent preclinical data confirm that progesterone reduces the behavioral response to stimulants.
Experimental and clinical psychopharmacology  •  2007  |  View Paper
High doses of progesterone might stimulate the growth of neurofibromas and deserve more caution.
BMC Cancer  •  2004  |  View Paper
Various agents that stimulate cellular protein phosphorylation (8-Br cAMP, okadaic acid, TPA) functionally synergize with progesterone to enhance progesterone-dependent PRtrans-activation in intact cells.
Breast Cancer Research and Treatment  •  2004  |  View Paper
However, progesterone at 10(-6) mol/l inhibited the stimulant effect of HC to a degree which was related inversely to the concentration of HC and the duration of the culture interval.
Scandinavian journal of haematology  •  1983  |  View Paper
Estrogen treatment causes growth of the duct system but not the alveoli in some rodents though the addition of progesterone stimulates alveolar growth.
Proceedings of the Royal Society of Medicine  •  1947  |  View Paper
We found that progesterone stimulates an [Ca2+]i increase in five different patterns: gradual increase, oscillatory, late transitory, immediate transitory, and sustained.
Biology of reproduction  •  2016  |  View Paper
Progesterone (PRO), a female hormone used in contraceptives, reduces stimulant use but its effects on tobacco addiction are unknown.
Behavioural Brain Research  •  2016  |  View Paper
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