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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Central Nervous System Stimulants and Niacin

Research Papers that Mention the Interaction

Our findings indicate that an interaction between muscarinic and nicotinic agonists synergistically stimulates anion secretion in mouse jejunal epithelial cells and identify a role for epithelial nicotinic receptors in anion secretion.
American journal of physiology. Cell physiology  •  2020  |  View Paper
Moreover, nicotinic acid prevents the up-regulation of ICAM-1 triggered by the pro-inflammatory cytokine TNF-α and stimulates the formation of endothelial tubes through GPER in HUVECs.
Cellular signalling  •  2014  |  View Paper
Preclinical and clinical studies suggest a facilitatory role of nicotinic agonists for stimulant addiction.
The American journal of drug and alcohol abuse  •  2009  |  View Paper
Niacin has also been shown to interfere with the cyclic AMP (cAMP)/protein kinase A (PKA) pathway and massively stimulate prostaglandin D2 (PGD2) formation.
Biochemical pharmacology  •  2004  |  View Paper
Nicotinamide was found to be nontoxic at the highest concentrations employed (10(-2)M) and suppressive over a relatively broad range (10(-…)M. The suppression appeared to be related to the magnitude of antigen- or mitogen-induced transformation and was apparent even when nicotinamide was added … hr after stimulant ….
Journal of immunology  •  1976  |  View Paper
NA potentiates the effect of 131I by increasing eNOS, which would in turn stimulate NO production, increasing thyroid blood flow and tissue damage via organic peroxides.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme  •  2006  |  View Paper
We have found that agents that stimulate protein kinases or that inhibit phosphoprotein phosphatases will decrease the rate of desensitization during repeated stimulation by either a nicotinic agonist or by a depolarizing concentration of KCI.'
Annals of the New York Academy of Sciences  •  1996  |  View Paper
Several agents which mimic cyclic AMP or stimulate cyclic AMP production in the ganglion enhance nicotinic transmission for several hours.
Brain Research  •  1991  |  View Paper