Possible Interaction: Central Nervous System Stimulants and Glucose

“It was concluded that dextrose and sucrose have the potential to stimulate fast and high insulin peaks, especially when combined with additional lactose.”

“It regulates glucose metabolism, stimulates glucose transport into cells and suppresses hepatic glucose production.”

“Insulin is produced by pancreatic β-cells, and once released to the blood, the hormone stimulates glucose uptake and suppresses glucose production.”

“Moreover, it stimulates glucose uptake by skeletal and cardiac muscle, and inhibits glucose production by the liver; consequently decreasing blood glucose levels.”

“Moreover, it stimulates glucose utilization in muscle and inhibits glucose production by the liver, consequently decreasing blood glucose levels.”

“The observation that glucose can both induce precocious maturation of the stimulus-secretion coupling and stimulate proliferation of the fetal beta-cell explains the intrauterine hyperinsulinemia and beta-cell hyperplasia of the offspring of diabetic mothers with relatively mild hyperglycemia.”

“It also increases the output of hepatic glucose, stimulates pancreatic bicarbonate secretion, relaxes the gall bladder and causes vasodilation2.”

“As these effects were blocked by an SGLT1 inhibitor and further analyses indicated that SGLT1 is expressed in macula densa cells, the researchers suggest that tubular glucose inhibits TGF and stimulates NO generation via SGLT1.”

“Using microperfusion and micropuncture techniques, they show that tubular glucose inhibits the TGF response in vitro and in vivo and stimulates the generation of nitric oxide (NO) at the macula densa.”

“Recently, it has been demonstrated that morning glucose ingestion stimulates pulsatile cortisol and adrenocorticotropic hormone (ACTH) secretion, thus elevating their mean concentrations.”

“Purpose of review‘Glucose effectiveness’ refers to the ability of glucose per se to suppress endogenous glucose production and stimulate glucose uptake.”