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“ Fluoride is also an effective inhibitor of prostaglandin E1-stimulated adenylate cyclase, while it markedly stimulates the basal activity of the enzyme.”
The Journal of biological chemistry • 1984 | View Paper
“Catalytic activity of the enzyme was retained with increasing animal age as evidenced by the ability of fluoride (10 mM) to stimulate basal activity 4-fold.”
“It was found that the fluorides definitely inhibit bone resorption; the cortico-steroids markedly increase osteoclasis and bone resorp-tions; while the tetracyclines stimulate osteogenesis and bone deposition.”
Acta odontologica Scandinavica • 1972 | View Paper
“The ingestion of large amounts of fluoride by experimental animals (500 ppm of fluoride in the drinking water) was reported to stimulate bone resorption 1 , and in addition to cause the formation of exostotic bony outgrowths 2 .”
“Cells grown in media with fluoride were more liable to autolysis, and walls isolated from them also showed enhanced autolytic sensitivity, even though added fluoride did not directly stimulate autolysins.”