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“ EDTA inhibits this system by 70% at a level of 10−3 M. This inhibition is partially reversed by Ca+2 ions which also markedly stimulate TUA activity.”
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine • 1961 | View Paper
“The following influences on the actual metabolic reactions could be deduced from the … reactions: SKF 525-A inhibits and phenobarbital pretreatment stimulates N -oxide demethylation; EDTA inhibits both the latter reaction and N -oxidation; EGTA and … N -oxide demethylation; SH-blocking agents inhibit C-oxidation and stimulate both … demethylation.”