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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Central Nervous System Stimulants and Edetic Acid

Research Papers that Mention the Interaction

EDTA inhibits this system by 70% at a level of 10−3 M. This inhibition is partially reversed by Ca+2 ions which also markedly stimulate TUA activity.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1961  |  View Paper
The following influences on the actual metabolic reactions could be deduced from the … reactions: SKF 525-A inhibits and phenobarbital pretreatment stimulates N -oxide demethylation; EDTA inhibits both the latter reaction and N -oxidation; EGTA and … N -oxide demethylation; SH-blocking agents inhibit C-oxidation and stimulate both … demethylation.
Archives of biochemistry and biophysics  •  1973  |  View Paper
Ca2+, Mg2+ and Mn2+ stimulate the activity up to 10 mM, but EDTA inhibits; higher concentrations of Ca2+ also inhibit.
The Biochemical journal  •  1976  |  View Paper
The presence of EDTA in the reaction mixture stimulates the system five- to ten-fold.
The Biochemical journal  •  1966  |  View Paper