Possible Interaction: Central Nervous System Stimulants and Copper

“It appears that H levels of both Zn and Cu interfered with intestinal absorption of Cu and/or stimulate post-absorption enterocyte sequestration of this mineral.”

“Plasma γ-globulin fraction proteins, copper and zinc cations, and metal complexes formed by these cations and human serum γ-globulin induce …/c mice at a level comparable to that induced by concanavalin A. Zinc bound to γ-globulin reduces by 25% and copper … stimulates by 1.… blast transformation.”

“The results of the present study show that exposure to copper at environmentally realistic levels or to chitosan at sublethal concentrations may significantly stimulate various aspects of immune functions in carp such as nonspecific cellular immunity, represented by total immunoglobulin level, ceruloplasmin activity, and oxidative activity of phagocytes.”

“We show that copper cooperatively stimulates catalytic activity of WNDP and that this effect requires the presence of both MBS5 and MBS6.”

“Hence, solutes that moderately stimulate mucosa-to-serosa fluid influx in a progressive manner, such as glucose polymers, may contribute to functionally increase Cu absorption.”

“Furthermore, the addition of the copper element could stimulate the expression of angiogenic genes, including the hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) in rat bone marrow stem cells (BMSCs).”

“The presence of Cu thus seems to stimulate diosgenin production.”