Possible Interaction: Central Nervous System Stimulants and Capsaicin

“ Capsaicin inhibits acid secretion, stimulates alkali and mucus secretion and particularly gastric mucosal blood flow which helps in prevention and healing of gastric ulcers.”

“ Capsaicin does not stimulate but inhibits acid secretion, stimulates alkali, mucus secretions and particularly gastric mucosal blood flow which help in prevention and healing of ulcers.”

“We hypothesized that regardless of environmental temperature, capsaicin application would stimulate heat loss and concomitantly deactivate heat conservation mechanisms, thus resulting in rectal temperature (Tre) and mean blood pressure decline due to excitation of heat‐sensitive TRPV1.”

“Lower concentrations (<250 &mgr;M) of capsaicin , but not other putative TRPV1 agonists, were shown to stimulate cell metabolic activity, whereas at concentrations >250 &mgr;M, all agonists decreased metabolic activity.”

“We demonstrate that CAP reduces viability and proliferation, and stimulates apoptotic death of NET cells.”

“The chief changes were TE shortening without vagal cooling, and TI prolongation during cooling to 7 degrees C. This suggests that capsaicin injected into the pulmonary circulation stimulates both the irritant and C-fiber receptors and the C-fiber afferents may prolong TI even when stimulated chemically.”