Possible Interaction: Central Nervous System Stimulants and Cannabinoids

“ Cannabinoids have been shown to inhibit prostaglandin synthesis, intensify pressor effects of endogenous amines like norepinephrine, and enhance the stimulant effects of amphetamine.”

“Many in vitro and in vivo experiments have shown that cannabinoids inhibit proliferation of cancer cells, stimulate autophagy and apoptosis, and have also a potential to inhibit angiogenesis and metastasis.”

“RESULTS It was found that subjects using both ca nabinoids an d sti mulants po inted to spirituality as a cause significantly more often than subjects taking only cannabinoids.”

“Thus, cannabinoids modulate brain reward systems closely involved in stimulants addiction, and provide further evidence that the cannabinoid system could be explored as a potential drug discovery target for treating addiction across different classes of stimulants.”