Possible Interaction: Central Nervous System Stimulants and Calcium Supplement

“Besides adenylate cyclase and phospholipase C activations, intracellular calcium increase also stimulates PLA2 activity and actin depolymerization, leading to membrane fusion.”

“It stimulates calcium release from the ryanodine calcium-release channel, inhibits calcium uptake by the sarcoplasmic reticulum calcium pump, and sensitizes the contractile proteins to calcium.”

“ Calcium acts to potentiate the response to gastrin and stimulates the release of gastrin from non-beta cell tumors.”

“Along the spectrum, it is likely that relative deficiencies of calcium and vitamin D interact with genetic and/or environmental factors to stimulate the development of rickets.”

“We recently demonstrated that suppressing 1α,25‐(OH)2‐D3 by increasing dietary calcium decreases adipocyte intracellular Ca2+ ([Ca2+]i), stimulates lipolysis, and inhibits lipogenesis.”

“ Ca2+ (50-100 microM) stimulate the binding by 10-20% and inhibit it by 20-30% at concentrations of 1-5 mM. Monoclonal antibodies to the glutamate receptor strongly suppress the L-[3H]glutamate binding by platelet membranes (IC50 = 300 nm).”

“While anti‐μ stimulation induces increased phosphatidylinositol (PI) turnover and [ Ca2+Ii fluxes, the latter two reagents confer an activation of B cells independent of the PI/Ca2+ pathway.”

“The extent to which calcium potentiated the ability of PTH to stimulate nephrogenous cAMP excretion correlated negatively with the basal nephrogenous cAMP excretion (r = -0.685, P less than 0.01).”

“Further, we compared the effect of the phagocytic challenge with that of Ca 2 + ionophores A23187 and ionomycin, lonophores were used since Ca z+ influx has been shown to stimulate the metabolism of exogenously added 20:4.”

“~ This latter metabolite increases intestinal absorption of calcium, stimulates bone resorption, and is also known to inhibit collagen synthesis in vitro?”