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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Celecoxib
supplement:
Tocotrienols
Research Papers that Mention the Interaction
“In addition, increasing lines of evidence has shown that tocotrienols can sensitize cancer cells to chemotherapeutic agents such as celecoxib , doxorubicin, erlotinib, gefitinib, gemcitabine, paclitaxel, statin etc.”
Tocotrienols: The promising analogues of vitamin E for cancer therapeutics“The triple combination of ATST, γ‐TT and CXIB showed a synergistic inhibition of cancer cell growth in MTT assays.”
“In contrast, combined treatment with subeffective doses of γ-tocotrienol and celecoxib resulted in a large decrease ErbB2-4 receptor levels and activation, a decrease in PGE(2) levels, and a corresponding increase in prostaglandin EP2 and EP4 receptor levels.”
Mechanisms Mediating the Synergistic Anticancer Effects of Combined γ-Tocotrienol and Celecoxib Treatment.
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