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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Cefotaxime and Epigallocatechin Gallate

Research Papers that Mention the Interaction

Flow cytometry showed that intracellular oxidative stress levels in the cell treated with a combination of EGCG and cefotaxime at sub-MICs were higher than those in the cells treated with either cefotaxime or EGCG at sub-MICs.
Flow cytometry showed that intracellular oxidative stress levels in the cell treated with a combination of EGCG and cefotaxime at sub-MICs were higher than those in the cells treated with either cefotaxime or EGCG at sub-MICs.
In contrast, the combination of cefotaxime and EGCG at their respective sub-MICs induced permanent cellular damages as well as continuous elongation in cells and eventually killed them.
PloS one  •  2012  |  View Paper
However, cefotaxime or imipenem in combination with higher concentration of EGCg (100 microg mL(-1)) only showed slight synergy against 2 of 17 Gram-negative rods.
The Journal of pharmacy and pharmacology  •  2003  |  View Paper