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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Cefotaxime
supplement:
Edetic Acid
Research Papers that Mention the Interaction
“Indifference to additive activity was observed for tested combinations and MIC value of cefotaxime or gentamicin in combination with EDTA was less than antibiotic alone in the most tested isolates.”
“The addition of the enzyme inhibitors ethylenediaminetetraacetic acid and p-hydroxymercuibenzoate reduced the metabolism of CTX in the presence of 10% hemolysis after 1 hr at 37 degrees C from 41% to 19% with ethylenediaminetetraacetic acid (0.45 mM) and to 0% with p-hydroxymercuibenzoate (10 mM).”
Cefotaxime metabolism by hemolyzed blood: quantitation and inhibition of the deacetylation reaction.
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