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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“We addressed the question of whether ATRA pretreatment could enhance the efficacy of polyI: C and, if so, would ATRA have any additional effects on this process.”
“… ATRA …: C strongly increased the expression of TLR3 and MDA5 in both WM35 and WM983A cells associated with significantly higher mRNA and secreted levels of interferon &…:C. Silencing of MDA5 by siRNA moderately affected IFN&bgr; secretion, whereas TLR3 knockdown interfered with both CXCL chemokine and IFN&bgr; production.”
Temporally designed treatment of melanoma cells by ATRA and polyI: C results in enhanced chemokine and IFN&bgr; secretion controlled differently by TLR3 and MDA5“During ATRA treatment, a significant decrease in the activity of serine/threonine phosphatases 2A, B and C occurred.”
“In unspecified mesoderm, … find that RA coordinately upregulates anterior 3′ Hox … from clusters A, B, and C , and downregulates posterior 5′ Hox genes from clusters A–D. However, hematopoietic development of mesoderm was inhibited by RA, and we find further that retinoids are entirely dispensable for hematopoiesis in vitro.”
The Retinoid Signaling Pathway Inhibits Hematopoiesis and Uncouples from the Hox Genes During Hematopoietic Development“Complexed poly I C induced the expression of the intracellular ds‐RNA sensor proteins, retinoic acid inducible gene I (RIG‐I), and melanoma differentiation‐associated gene 5 (MDA‐5).”
“Moreover, the resorption induced in calvaria by a pretreatment with PTH or retinoic acid is inhibited by a further culture with catechin.”
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