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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Catechin
drug:
Paclitaxel
Research Papers that Mention the Interaction
“Moreover, cotreatment of poly I C and PTX acted synergistically to induce cell apoptosis of HCT‐8/PTX via upregulating the expression of TLR3 and its molecular chaperone UNC93B1, assisting in the secretion of IFN‐β.”
“Notably, a combination of poly I C and PTX synergistically inhibited the PTX‐resistant tumor growth in vivo without side effects.”
Toll‐like receptor 3 agonist poly I:C reinforces the potency of cytotoxic chemotherapy via the TLR3‐UNC93B1‐IFN‐β signaling axis in paclitaxel‐resistant colon cancer“Nine phenolic antioxidants (+)-catechin , (-)-epicatechin, fisetin, gallic acid, morin, myricetin, naringenin, quercetin and resveratrol) were tested for inhibition of paclitaxel metabolism.”
“In all the 3 experimental groups, that is A, C , and AC groups, the ability to inhibit platelet aggregation was weakened as paclitaxel concentration increased.”
“In addition, combination treatment with poly I C and paclitaxel more significantly inhibited cell proliferation compared with poly I:C or paclitaxel alone.”
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