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Last Updated: 3 years ago

Possible Interaction: Catechin and Nitric Oxide

supplement:

Catechin

Research Papers that Mention the Interaction

Catechins cause an increase in the activity of endothelial nitric oxide synthase (eNOS) and increased production of nitric oxide (NO) and decrease in blood pressure.
Postepy higieny i medycyny doswiadczalnej  •  2017  |  View Paper
Here, we demonstrate that catechin and quercetin have the potential to down-regulate the initial signalling molecule NF-κB which may further inhibit the downstream cascade including TNF-α and NO.
Innate immunity  •  2012  |  View Paper
(+)-Catechin inhibited the production of NO and TNF-α in LPS-stimulated primary macrophages.
Taken together, these results demonstrate that (+)-catechin inhibits tumour-specific angiogenesis by regulating the production of pro- and anti-angiogenic factors such as pro-inflammatory cytokines, nitric oxide , VEGF, IL-2 and TIMP-1.
Innate immunity  •  2008  |  View Paper
On immunomodulatory properties, catechin , epigallocatechin (EGC), naringenin, and fisetin repressed NO production and TNF-a secretion.
Archives of pharmacal research  •  2005  |  View Paper
The (−)-epicatechin stereoisomer catechin was only partially able to stimulate nitric oxide production in cells.
Hypertension  •  2010  |  View Paper
Treatment of platelets with quercetin and catechin resulted in an increase of NO and also down-regulated the expression of GpIIb/IIIa glycoprotein.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology  •  2006  |  View Paper
Our results demonstrate that NO inhibits Cl-/OH- exchange activity in Caco-2 cells via cGMP-dependent protein kinases G (PKG) and C (PKC) signal-transduction pathways.
American journal of physiology. Gastrointestinal and liver physiology  •  2002  |  View Paper
The results showed that C is the most effective inhibitor of LPS-induced NO production.
The Chinese journal of physiology  •  2021  |  View Paper
Daturmetesides A, C and D moderatelylowered the NO production with IC50 values ranging from 17.05 ± 0.35 to 24.88 ± 0.93 μM.
Steroids  •  2020  |  View Paper
Altogether, the results indicate that (+)-catechin , at nM concentrations, inhibits mitochondrial complex I activity, leading to membrane potential decline and consequently to reduction in H2O2 and NO production rates.
Food & function  •  2019  |  View Paper
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