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Last Updated: 3 years ago
supplement:
Catechin
Research Papers that Mention the Interaction
“Pretreatment … with Nω-nitro-l-arginine methylester (L-NAME, an inhibitor of nitric oxide synthase) or 1H-[1,2,4] oxadiazolo[4,3-a]quinoxalin-… (ODQ, an inhibitor of soluble guanylate cyclase), resulted in a significant change of relaxant effect induced by catechin , and a slight … cryptostrobin-induced relaxation.”
Cryptostrobin and catechin isolated from Eugenia mattosii D. Legrand leaves induce endothelium-dependent and independent relaxation in spontaneously hypertensive rat aorta.“Mechanical removal of endothelium, blockade of soluble guanylyl cyclase by 1H-1,2,4-… (ODQ, 1 and 5 microM) or inhibition of nitric oxide (NO) synthase by N(G)-nitro-L-arginine (L-NAME, 50 … response to catechin ; moreover, the NO donor S-nitroso-… the vasorelaxant responses to EGCG.”
“ N(G)-nitro-L-arginine methyl ester (10(-5) M) enhanced the contractile responses in the PA rings from both C and HLU animals and completely abolished the differential responses to PE and U4 in HLU vs. C animals.”
“ L-NAME enhanced Fmax of AngII contractions by about 75% in C, 120% in I1, and 74% in I2 groups; accordingly, it augmented the final steady-state force in C and I1 but not in I2.”
“Similarly, L-NAME increased Fmax (30-40%) of AVP and ET1 contractions in C and I1 groups but failed to do so in contractions of I2 group.”
“A supramaximal dose of L-NAME (10 mg/kg body wt) increased sBP in C and D rats to a similar degree.”
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