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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Catechin
drug:
Ketoprofen
Research Papers that Mention the Interaction
“More importantly, the treatment of Sprague-Dawley rats with catechin (35 mg/kg/day) prior to the administration of ketoprofen (50 mg/kg/day) successfully inhibited oxidative damage and reversed the impairment of the antioxidant system in the intestinal mucosa.”
Catechin protects against ketoprofen-induced oxidative damage of the gastric mucosa by up-regulating Nrf2 in vitro and in vivo.“Conventional suppository and liquid suppository without C significantly gave faster time to reach the maximum plasma concentrations of KP.”
“With regard to the results of … studies, the AUC6→14 values of KP in liquid … containing C are significantly higher than those in liquid suppository without C. MRT0→24 and MRT0→∞ values of … suppository containing C are significantly higher than those in liquid suppository without C and conventional suppository.”
In vitro–in vivo evaluation of in situ gelling and thermosensitive ketoprofen liquid suppositories
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