Possible Interaction: Catechin and Insulin

“Objective: Vitamin E and C given separately improve insulin sensitivity due to an inhibitory effect on oxidative stress and inflammation, however their combined effect on glucose control and inflammation is unknown.”

“In vitro studies with mouse cardiomyocyte HL-1 cells showed that insulin suppressed the expression of miR-29a, b and c and increased MCL-1 mRNA.”

“In comparison to 0100–0300 h, mean insulin infusion rates required to maintain blood glucose values between 105 and 120 mg/dl during the prebreakfast period increased by 66 ± 25% during C , and 42 ± 12% during SRIF + G when serum growth hormone was suppressed to <0.75 ng/ml.”

“Circulating levels of insulin , IGF-1 and leptin were significantly higher in C and KO mice exposed to high-fat diet compared to those in the same strain exposed to standard diet.”

“ Insulin inhibited food intake in C but not in R females.”

“ Insulin produced a consistent but incomplete inhibition of binding in both C and M, of 75% and 67% respectively.”

“These studies indicate that insulin rapidly stimulates the incorporation of phosphate into nuclear lamins A and C in quiescent BHK-21 fibroblasts.”

“Procyanidol oligomers and (+) catechin bound to insoluble elastin markedly affect its rate of degradation by elastases.”

“Interactions between the insoluble fractions of coffee infusions and catechins were synergistic for espresso and additive/antagonistic for the other infusions.”

“The ·OH yield achieved using insoluble tannins from Pinus radiata bark was higher than that achieved using catechin to drive the Fenton reaction.”