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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Catechin
drug:
Indomethacin
Research Papers that Mention the Interaction
“Poly I C increased prostaglandin E2 levels in the cerebrospinal fluid of the animals which was also reduced by indomethacin.”
Central mediators involved in the febrile response induced by polyinosinic–polycytidylic acid: Lack of involvement of endothelins and substance P“In contrast to ebselen, indomethacin inhibited SPLT migration into the inflamed joints as well as to the dermal inflammation induced by poly I: C and a delayed-type hypersensitivity reaction (DTH).”
“Furthermore, the fever induced by intrahypothalamic injection of IFN or poly I C was reduced by pretreatment of animals with a systemic dose of indomethacin (an inhibitor of all prostaglandins formation) or cycloheximide (an inhibitor of protein synthesis).”
“The combination of poly I C and indomethacin together, however, led to the greatest inhibition in tumor growth, and in some instances, to tumor regression.”
“This action of poly I C was prevented by concomitant administration of indomethacin.”
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