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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Catechin and Fluorouracil

supplement:

Catechin

Research Papers that Mention the Interaction

In addition, the combination of 5FU and catechin showed additional cytotoxicity and induced reactive oxygen species (ROS)-mediated apoptosis in SNU620/5FU cells.
International journal of molecular sciences  •  2021  |  View Paper
Dual color flow cytometric analysis revealed that (+)-catechin reversed the reduction of the population of leukocytes (CD11b+ monocytes, Gr-1+ granulocytes and CD3+ T and CD45RA+ B lymphocytes) in whole blood, spleen and bone marrow caused by 5-FU.
These findings suggest that (+)-catechin selectively enhances the recovery of the population of granulocytes reduced by 5-FU in mice.
Toxicology  •  2004  |  View Paper
Analogous studies were performed on 5FU-green tea extract mixtures, showing that 5FU leads to complexes not only with EGCG but also with other catechins.
Journal of mass spectrometry : JMS  •  2021  |  View Paper