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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Catechin and Diazepam

supplement:

Catechin

Research Papers that Mention the Interaction

The initial rate of absorption of diazepam contained in the drink was increased by C (AUC 0–1 h C: 328 µg h 1−1, P: 253 µg h 1−1, but there was no change in overall bioavailability.
European Journal of Clinical Pharmacology  •  2004  |  View Paper
However, only C had a clear inhibitory effect on the elimination of diazepam while R,O,N and F did not affect the pharmacokinetics of diazepam.
Pharmacology & therapeutics  •  1987  |  View Paper
However, in man, only C inhibited the hepatic elimination of diazepam by about 45% while R, O, N and F did not affect the pharmacokinetics of diazepam.
Biochemical pharmacology  •  1986  |  View Paper