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“ Actinomycin D at a concentration of 0.25 μg/ml inhibited the synthesis of D, C and A. Cycloheximide (0.19 μg/ml) reduced the synthesis of D, C and rRNA to about 50% of control whereas 5S RNA synthesis was only slightly inhibited and tRNA synthesis was unaffected.”
“ Actinomycin D inhibited activation of lysosomal cathepsins A, B, C , D, H and L in peritoneal macrophages, caused by T-dependent antigen (sheep erythrocytes), of mice CBA X C57BL/6 strain.”
“When actinomycin D (1 and 2 mg/kg) or cycloheximide (6 mg/kg) was given twice, simultaneously with papyriogenin A or C , during the latent period for the manifestation of the anti-inflammatory effect, the anti-inflammatory effects of papyriogenin A and C were blocked completely by s.c.”
Journal of pharmacobio-dynamics • 1983 | View Paper
“Pretreatment of the cells with adriamycin, actinomycin D , and puromycin increased the sensitivity of the cells to killing by rabbit anti-P815 antibody plus guinea pig C , but not by allogeneic P815-sensitized spleen cells.”