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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Catechin
drug:
Collagenases
Research Papers that Mention the Interaction
“Heating the joint cavity up to 42 deg C can inhibit the enzymatic effect of collagenase , oxygenase, and other enzymes playing a role in the inflammatory process.”
Deep heat in the treatment of inflammatory joint disease.“Both catechin and EGCG exhibited competitive mode of inhibition against collagenase.”
“ Catechin and EGCG treated collagen exhibited 56 and 95% resistance, respectively, against collagenolytic hydrolysis by collagenase.”
“The kinetics of inhibition of collagenase by catechin and EGCG has been deduced from the extent of hydrolysis of (2-furanacryloyl-L-leucyl-glycyl-L-prolyl-L-alanine), FALGPA.”
“Whereas direct interaction of catechin and EGCG with collagenase exhibited 70 and 88% inhibition, respectively, to collagenolytic activity of collagenase against collagen and the inhibition was found to be concentration dependent.”
Role of green tea polyphenols in the inhibition of collagenolytic activity by collagenase.
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