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Last Updated: 2 years ago

Possible Interaction: Caseins and Spermine

supplement:

Caseins

Research Papers that Mention the Interaction

Only at low Mg2+ concentration spermine enhanced by 68% the rate of casein phosphorylation.
European journal of biochemistry  •  1985  |  View Paper
Nuclear casein kinase II activity was present in … fractions as evidenced by the capacity of spermine to stimulate (ED50 = 0.19 mM) and heparin to … (ID50 = 0.09 μg/ml) the phosphorylation of casein ; further, the phosphotransferase activity could be purified by … casein-agarose and spermine-agarose affinity chromatography.
Molecular and Cellular Biochemistry  •  2004  |  View Paper
The Vmax of CK-1 for both casein and ATP is increased by spermine while the Km remains unchanged by the polyamine.
Archives of biochemistry and biophysics  •  1988  |  View Paper
Abstract: An analysis of the effects of polyamines on protein phosphorylation … fractions of the pupal brain of Manduca sexta showed that spermine elicited an … in casein phosphorylation in a dose‐dependent manner (maximum three‐ to fourfold at 2.… mM), whereas spermidine was less effective and putrescine was without effect.
Journal of neurochemistry  •  1987  |  View Paper
These studies were conducted by holding ionic strength constant at 0.10 M. At low Mg2+ (2.5 mM), activation by spermine resulted in a 33% decrease in the apparent Km for casein.
Archives of biochemistry and biophysics  •  1984  |  View Paper
When casein was used as a substrate, spermine stimulated the enzyme activity 7.3-fold at 2 mM, and a 6.5-fold stimulation was observed with 6 mM spermidine.
Biochemistry  •  1982  |  View Paper
Phosphorylation of casein was stimulated by polyamines, particularly spermine.
The Journal of biological chemistry  •  1981  |  View Paper
In the presence of excess Mg2+, phosphorylation of casein by the kinase was stimulated by spermine (1-5 mM) and was inhibited completely by 0.1 microgram/ml heparin.
The apparent Km for casein was reduced in the presence of spermine.
Medical biology  •  1981  |  View Paper
Spermine decreased the apparent Km for casein and increased the maximum velocity of the reaction.
The Journal of biological chemistry  •  1984  |  View Paper
Phosphorylation of casein is stimulated by spermine.
European journal of biochemistry  •  1984  |  View Paper