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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Leucine supplementation to the 3 % casein diet did not affect genes related to lipid metabolism, but inhibited the decrease in p62, the increase in LC3-II, and the increase in Xbp1 splicing levels in the liver.”
“RESULTS Ca ein in gestion increased pla sma leucine an d phenylalanine concentrations and L-[1-(13)C]-phenylalanine enrichments, with a more rapid rise after Cas vs. Cas+Serum.”
“Postprandial leucine balance over 7 h was higher after the slow than after the fast meals ( CAS : 38 +/- 13 vs. AA: -12 +/- 11, P < 0.01; RPT-WP: 87 +/- 25 vs. WP: 6 +/- 19 micromol/kg, P < 0.05).”
The digestion rate of protein is an independent regulating factor of postprandial protein retention.“The hydrophobic amino acid, leucin counteracted the attachment of casein.”
“Consumption of more than 2% leucine in a 6% casein diet suppressed food intake and caused growth retardation in a dose-dependent manner, but this was not seen in a 12% or 40% casein diet.”
Down Regulation of Asparagine Synthetase and 3-Phosphoglycerate Dehydrogenase, and the Up-Regulation of Serine Dehydratase in Rat Liver from Intake of Excess Amount of Leucine Are Not Related to Leucine-Caused Amino Acid Imbalance.“Furthermore, LPL activity in adipose tissue of rats fed CP or L was 1.6-fold lower than that of rats fed CAS.”
“However, feeding of a 5% casein diet supplemented with leucine (1.15%) reduced muscle weight loss and MeHis release.”
“With casein , correlations were significant for threonine, valine, isoleucine and leucine.”
“ Leucine uptake was significantly decreased in casein hydrolysatefed animals when compared to that in casein-fed animals in both the proximal and distal bowel, again when expressed as a percent change from the control values.”
“In rats fed for 2 weeks on a 10% casein diet supplemented with 5% leucine , the hepatic NAD content was lowered when comparing with the control rats pair-fed on the 10% casein diet.”
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