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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caseins
drug:
Cholecystokinin
Research Papers that Mention the Interaction
“ Casein infusion tended to increase plasma CCK concentration on both days of sampling, and increased plasma GLP-1 and insulin concentration on day 1 of infusion.”
“Protein hydrolysates from various origins (meat, casein , soybean, and ovalbumin; 0.5-1%, wt/vol) dose dependently increased CCK release.”
“Intraduodenal infusion of casein increased the plasma CCK concentration and the pancreatic amylase output.”
“Duodenal infusion of casein resulted in elevation of plasma CCK from fasting level of 0.5 +/- 0.1 to 3.8 +/- 0.4 pM. Casein hydrolysate, calcium, and glucose did not elevate plasma CCK.”
“Intraduodenal administration of casein in a dose of 400 mg/h caused significant increases in plasma CCK concentration and pancreatic secretion of juice volume and outputs of amylase and trypsin.”
“Prior administration of the CCK antagonist significantly attenuated the increase in plasma insulin and glucagon after casein infusion.”
“Solutions of 18% casein and 0.2% soybean trypsin inhibitor caused prompt increases in plasma CCK levels from 0.5 +/- 0.2 to 7.9 +/- 1.9 and 8.0 +/- 2.0 pM, respectively, within 5 min of orogastric administration.”
Proteins but not amino acids, carbohydrates, or fats stimulate cholecystokinin secretion in the rat.“The levels of serum cholecystokinin (CCK) and secretin in the IC treatment group were higher compared to the other treatment groups (p<0.05).”
Effect of Oral Administration of Intact Casein on Gastrointestinal Hormone Secretion and Pancreatic α-Amylase Activity in Korean Native Steer“Protein hydrolysates from various origins (meat, casein , soybean, and ovalbumin; 0.5-1%, wt/vol) dose dependently increased CCK release.”
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