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Last Updated: a year ago

Possible Interaction: Carrageenan and Tempol





Research Papers that Mention the Interaction

The effects of carrageenan were inhibited by the combination of the free radical inhibitor Tempol and BCL10 siRNA, which had no impact on the HFD-mediated increase.
Journal of diabetes research  •  2019  |  View Paper
Corroborating the effect of tempol in the KO2 model, tempol also inhibited carrageenan and CFA inflammatory hyperalgesia.
BioMed research international  •  2017  |  View Paper
TEMPOL (60 mg/kg, 15 min before peroxynitrite-carrageenan) inhibited the peroxynitrite enhancement of carrageenan hyperalgesia when tested at 60 min after injection of the cocktail.
European journal of pharmacology  •  2006  |  View Paper
Tempol (100mg/kg i.p 30min prior to carrageenan administration) significantly attenuated the degree of pleuritis caused by carageeenan (all parameters measured).
Free radical research  •  2004  |  View Paper
Furthermore, treatment of rats with tempol significantly reduced (i) the formation of peroxynitrite, (ii) the DNA damage, (iii) the impairment in mitochondrial respiration, and (iv) the fall in the cellular level of NAD(+) observed in macrophages harvested from the pleural cavity of rats treated with carrageenan.
European journal of pharmacology  •  2000  |  View Paper