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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Carrageenan
drug:
Substance P
Research Papers that Mention the Interaction
“This reduction occurred when SP was administered either before or after the carrageenan injection.”
Supraspinal injection of Substance P attenuates allodynia and hyperalgesia in a rat model of inflammatory pain“Synergistic increases in the exudate formation were observed when a sub-optimal quantity of carrageenan was injected with SP.”
“Subcutaneous injection of carrageenan into the rat paw caused a significant increase in substance P levels, which preceded the onset of inflammation.”
“While injection of substance P alone caused mild edema, coadministration of submaximal doses of carrageenan and substance P resulted in a synergistic exacerbation in the degree of inflammation.”
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