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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Carrageenan
drug:
Pentoxifylline
Research Papers that Mention the Interaction
“ Pentoxifylline also inhibited the mechanical hypernociception in rats induced by the intraplantar injection of either carrageenin (−81%), bradykinin (−56%) or tumor necrosis factor α (TNF‐α; −46%), but not that induced by interleukin‐1β (IL‐1β) or prostaglandin E2 (PGE2).”
Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain“ PTX (0.6 mg per paw) given with carrageenan into the rat hind paw reduced the oedema response with a maximal effect of 33.4% at 1h following carrageenan.”
“administration of PTX (36 or 72 mg kg(-1)) 30 min prior to carrageenan reduced the paw oedema response in dose-dependent manner with a maximal effect of 18.9 and 40.1%, respectively, at 2h post-carrageenan (P<0.001 and <0.001 at respective doses).”
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