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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Carrageenan and Dexmedetomidine

Research Papers that Mention the Interaction

Acute inflammatory nociception was induced by an intraplantar injection of 1% carrageenan into the hindpaws of rats, and dexmedetomidine was also injected combined with carrageenan.
As the results, the intraplantar injection of carrageenan with over 10 μM dexmedetomidine significantly increased AUC, compared to that with only carrageenan injection.
European journal of pharmacology  •  2015  |  View Paper
There was a mild increase in potency of the selective alpha-2 adrenoceptor agonist dexmedetomidine following carrageenan (ED50 = 1 microgram).
Neuroreport  •  1994  |  View Paper