Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a month ago

Possible Interaction: Carrageenan and Dexamethasone

supplement:

Carrageenan

Research Papers that Mention the Interaction

Pretreatment of the rats with dexamethasone (DEXA) prior to carrageenin injection or incubation of PMN with the glucocorticoid in vitro partially inhibited the spontaneous release of NO.
Mediators of inflammation  •  1995  |  View Paper
Dexamethasone (0.3 mg/kg, i.p.) reduced BK-(1–5) levels (by 78%) and decreased plasma exudation (by 70%) 3 h after carrageenin.
Inflammation Research  •  1996  |  View Paper
Oral administration of the EOAS (20 and 200 mg/kg) and subcutaneous injection of dexamethasone (0.5 mg/kg, reference drug) significantly inhibited carrageenan- and complete Freund's adjuvant-induced mouse paw edema.
Journal of medicinal food  •  2013  |  View Paper
Hyperalgesic … carrageenin (100 micrograms), bradykinin (500 ng), TNF alpha (2.5 pg), IL-1 beta (0.5 pg), and IL-6 (… to IL-8 (0.1 ng), PGE2 (100 ng) and dopamine (10 micrograms), were inhibited by pretreatment with dexamethasone (0.5 mg kg-1, …-5.0 micrograms/paw).
carrageenin (100 micrograms), bradykinin (500 ng), TNF alpha (2.5 pg), IL-1 beta (0.5 pg), and IL-6 (1.0 … not responses to IL-8 (0.1 ng), PGE2 (100 ng) and dopamine (10 micrograms), were inhibited by pretreatment with dexamethasone (0.5 mg …, subcutaneously, s.c.,
British journal of pharmacology  •  1997  |  View Paper
Although dexamethasone significantly suppressed paw edema induced by carrageenan , wogonin had no effect on the anti-inflammatory action of dexamethasone.
Annals of the New York Academy of Sciences  •  2007  |  View Paper
Finally, carrageenan administration produced a time-dependent increase in cellular infiltration into the pouch exudate that was inhibited by dexamethasone and NOS inhibitors.
The Journal of clinical investigation  •  1995  |  View Paper
Exudate volume and leukocyte number in the pleural cavity at 3 h after the carrageenin injection were significantly reduced by the pretreatment with indomethacin or dexamethasone.
European journal of pharmacology  •  1994  |  View Paper
The exudate volume was also significantly decreased when indomethacin, a cyclooxygenase inhibitor, or dexamethasone , a steroidal antiinflammatory drug, was coinjected with carrageenan.
Inflammation  •  1993  |  View Paper
Pretreatment with dexamethasone (0.1 mg kg-1) or colchicine (2 mg kg-1), likewise suppressed carrageenin paw oedema.
British journal of pharmacology  •  1993  |  View Paper
K-252a (1-100 mg/kg p.o.), as well as dexamethasone (1 mg/kg s.c.), showed remarkable inhibitory effects on rat paw edema induced by carrageenin , zymosan, PAF, and antigen-antibody reaction (passive Arthus reaction) and on the croton oil-induced rat ear edema.
Arzneimittel-Forschung  •  1988  |  View Paper
Show More