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Last Updated: 2 years ago

Possible Interaction: Carrageenan and Dexamethasone



Research Papers that Mention the Interaction

Oral administration of the EOAS (20 and 200 mg/kg) and subcutaneous injection of dexamethasone (0.5 mg/kg, reference drug) significantly inhibited carrageenan- and complete Freund's adjuvant-induced mouse paw edema.
Journal of medicinal food  •  2013  |  View Paper
carrageenin (100 μg), bradykinin (500 ng), TNFα (2.5 pg), IL‐1β (0.5 pg), and IL‐6 (1.0 ng), … not responses to IL‐8 (0.1 ng), PGE2 (100 ng) and dopamine (10 μg), were inhibited by pretreatment with dexamethasone (0.5 mg kg−…, subcutaneously, s.c.,
British journal of pharmacology  •  1997  |  View Paper
Although dexamethasone significantly suppressed paw edema induced by carrageenan , wogonin had no effect on the anti‐inflammatory action of dexamethasone.
Annals of the New York Academy of Sciences  •  2007  |  View Paper
The exudate volume was also significantly decreased when indomethacin, a cyclooxygenase inhibitor, or dexamethasone , a steroidal antiinflammatory drug, was coinjected with carrageenan.
Inflammation  •  2004  |  View Paper
When administered at 2 h postcarrageenin , there was no effect at 3 h; but at 6 h, dexamethasone significantly reduced the swelling.
Inflammation  •  2004  |  View Paper
Dexamethasone dramatically attenuated both carrageenan hyperalgesia and inflammation.
Brain Research  •  2003  |  View Paper
Finally, carrageenan administration produced a time-dependent increase in cellular infiltration into the pouch exudate that was inhibited by dexamethasone and NOS inhibitors.
The Journal of clinical investigation  •  1995  |  View Paper
Exudate volume and leukocyte number in the pleural cavity at 3 h after the carrageenin injection were significantly reduced by the pretreatment with indomethacin or dexamethasone.
European journal of pharmacology  •  1994  |  View Paper
The anti-inflammatory effect of dexamethasone in carrageenin rat paw oedema was significantly reduced or abolished by local injection of 0.5-2.5 mg of the antiglucocorticoid progesterone, or of 5 micrograms cycloheximide, or of 2.5 micrograms actinomycin D, into the oedematous area.
International journal of tissue reactions  •  1984  |  View Paper
These proteins, as well as dexamethasone itself, inhibited the hind-paw rat oedema induced by carrageenin.
European journal of pharmacology  •  1984  |  View Paper
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