“In contrast, BQ-123 (150 pmol/paw) failed to affect paw edema induced in nonsensitized mice by histamine (100 μg/paw), serotonin (100 μg/paw), or zymosan (500 μg/paw), but significantly reduced edema induced by carrageenan (300 μg/paw) by 30% (p < 0.05).”