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Discover Supplement-Drug Interactions
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Last Updated: 3 months ago
drug:
Carprofen
supplement:
Serum Albumin, Human
Research Papers that Mention the Interaction
“A remarkable stereodifferentiation has been observed in the interaction between the excited triplet state of carprofen CP ) and human serum albumin (HSA).”
Human serum albumin-mediated stereodifferentiation in the triplet state behavior of (S)- and (R)-carprofen.“Circular dichroism data suggested different mechanisms for the high affinity and the low affinity binding of carprofen to HSA.”
“The S(+)-enantiomer of carprofen showed slightly higher affinity for HSA than its corresponding antipode by both methods.”
“ Carprofen gives rise to different CD spectra at lower (1:1) and higher (3:1) molar ratios to HSA , indicating different mechanisms for the binding of this drug to its high and low affinity sites on HSA.”
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