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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Carprofen and Serum Albumin, Human

Research Papers that Mention the Interaction

A remarkable stereodifferentiation has been observed in the interaction between the excited triplet state of carprofen CP ) and human serum albumin (HSA).
Journal of the American Chemical Society  •  2004  |  View Paper
Circular dichroism data suggested different mechanisms for the high affinity and the low affinity binding of carprofen to HSA.
The S(+)-enantiomer of carprofen showed slightly higher affinity for HSA than its corresponding antipode by both methods.
Biochemical pharmacology  •  1993  |  View Paper
Carprofen gives rise to different CD spectra at lower (1:1) and higher (3:1) molar ratios to HSA , indicating different mechanisms for the binding of this drug to its high and low affinity sites on HSA.
Biochemical pharmacology  •  1993  |  View Paper