Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Carotenoids and Tocopherols





Research Papers that Mention the Interaction

Previous studies suggest that carotenoids and tocopherols (vitamin E compounds) may be inversely associated with prostate cancer risk, yet little is known about how they affect prostate cancer progression and survival.
Cancer research  •  2009  |  View Paper
In vitro studies investigating the synergistic effects of mixtures of carotenoids and tocopherols have been hindered due to the difficulty of solubilising these lipophilic compounds.
The British journal of nutrition  •  2004  |  View Paper
Tocopherols and carotenoids were significantly correlated with each other (P<0.05) in maternal and cord plasma.
European Journal of Clinical Nutrition  •  1999  |  View Paper
Carotenoids were positively correlated with plant height as well as foliar and floral traits but negatively correlated with tocopherols.
Planta  •  2019  |  View Paper
Carotenoids and tocopherols showed weak correlation with 2,2-diphenyl-1-picrylhydrazyl (DPPH) activity (r=0.4893 and 0.3259, respectively), but good correlation when combined (r=0.6688), suggesting they may act synergistically.
Food chemistry  •  2014  |  View Paper
There is a body of evidences demonstrating, in biological systems, a cooperative interaction between tocopherols and carotenoids.
Free radical research  •  2006  |  View Paper
The tocopherol-deficient mutants were also more susceptible to HL treatment in the presence of sublethal levels of norflurazon, an inhibitor of carotenoid synthesis, suggesting carotenoids and tocopherols functionally interact or have complementary or overlapping roles in protecting Synechocystis sp. strain PCC 6803 from lipid peroxidation and HL stress.
Plant Physiology  •  2005  |  View Paper