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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Carotenoids
drug:
Nitric Oxide
Research Papers that Mention the Interaction
“The study also recorded that six carotenoids considerably inhibited lipopolysaccharide (LPS)-induced nitric oxide ( NO ) production, tumor necrosis factor-alpha (TNF-α), and lipid peroxidation in PBMCs.”
Diapolycopenedioic-acid-diglucosyl ester and keto-myxocoxanthin glucoside ester: Novel carotenoids derived from Exiguobacterium acetylicum S01 and evaluation of their anticancer and anti-inflammatory activities.“All the carotenoids significantly improved basic endothelial function as measured by increased nitric oxide and decreased endothelin (ET-1) release.”
“Highest NO inhibitory effect was detected in the chloroform fraction, and the active compound was identified as fucoxanthin, a kind of carotenoid available in brown algae evidenced high correlation with the inhibitory effect of NO production (r(2)=0.9511).”
Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages.“We suppose that nitric oxide causes a conformational transition of carotenoids in the axon plasmatic membrane and the membranes of cytosomes.”
“The reaction between carotenoids and nitric oxide led to the decreasing absorption between 400 and 540 nm and the concomitant appearance of the new absorption peaks between 330 and 395 nm.”
“ Carotenoid , tocopherol, flavonoid and ascorbate biosynthesis were differentially affected by NO , resulting in overaccumulation of ascorbate (25%) and flavonoids (60%) and impaired lycopene production.”
Multifaceted roles of nitric oxide in tomato fruit ripening: NO-induced metabolic rewiring and consequences for fruit quality traits.
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