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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Carotenoids
supplement:
Magnesium
Research Papers that Mention the Interaction
“Thus, at physiological ranges, calcium and magnesium could negatively impact carotenoid bioavailability, while for zinc, negative effects were only seen at supplemental concentrations.”
Negative effects of divalent mineral cations on the bioaccessibility of carotenoids from plant food matrices and related physical properties of gastro-intestinal fluids.“ Magnesium may reduce carotenoid bioavailability by forming insoluble complexes with bile salts/fatty acids, inhibiting micelle formation.”
“The impact of magnesium on carotenoid bioaccessibility was modulated mainly by bile concentration, with samples digested with 1mM of bile being more susceptible to inhibitory effects of magnesium than those digested with 8mM (p<0.001).”
“Thus, magnesium was found to potentially interfere with carotenoid bioaccessibility at various physiologically plausible conditions.”
Magnesium affects spinach carotenoid bioaccessibility in vitro depending on intestinal bile and pancreatic enzyme concentrations.
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