Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a year ago

Possible Interaction: Carotenoids and Lycopene

supplement:

Carotenoids

supplement:

Lycopene

Research Papers that Mention the Interaction

After 26 d of … of the drink, plasma carotenoid levels increased …: concentrations of lycopene were 1·7-fold higher (P<0·0001); of phytofluene were 1·6-fold higher (P<0·0001); … phytoene were doubled (P<0·0005); of β-carotene were 1·3-fold higher (P<0·05).
British Journal of Nutrition  •  2005  |  View Paper
It is also clear that the form of lycopene used (purified versus food sources), dose of lycopene and concomitant use with other carotenoids and antioxidants, duration of exposure, specific target populations, and stage of disease appear to play a major role in determining agonistic or antagonistic effects.
Journal of the Society for Integrative Oncology  •  2008  |  View Paper
After an intervention period of 8±2 months, lycopene concentration increased from 67.5±30 to 121.8±102 μg/l (P=0.025).Conclusion Carotenoid concentrations are dramatically decreased in CP, especially lycopene in CP patients with vascular disease.
European Journal of Clinical Nutrition  •  2011  |  View Paper
Significant reductions in serum carotenoids (P < 0.05 vs. control) were demonstrated for some alleles: beta-carotene and lycopene in E2 and E4; alpha-carotene in E3; cryptoxanthin in E3 and E4; zeaxanthin in E4; lycopene in E2 and E4; and lutein in E2 carriers.
The Journal of nutrition  •  2009  |  View Paper
The inverse associations of lycopene and the sum of carotenoids with the risk of advanced disease may involve a protective effect, an association of dietary choice with delayed detection of prostate cancer, reverse causality, or other factors.
The American journal of clinical nutrition  •  2007  |  View Paper
The results for lycopene were, however, discordant from those of the other carotenoids.
British Journal of Nutrition  •  2006  |  View Paper
Thus, cellular carotenoids inhibit proliferation, and for lycopene at least, this may involve cell differentiation.
The Journal of nutrition  •  2005  |  View Paper
At the end of the experiment, treatment of the animals with LUT or LYC resulted in an increase in the respective liver carotenoid concentrations (P < 0.05).
Nutrition and cancer  •  2003  |  View Paper
After administration of the carotenoid association, beta-carotene distribution in the four organs was strongly inhibited by lycopene.
In vivo  •  1998  |  View Paper
Carotenoid , tocopherol, flavonoid and ascorbate biosynthesis were differentially affected by NO, resulting in overaccumulation of ascorbate (25%) and flavonoids (60%) and impaired lycopene production.
Journal of experimental botany  •  2020  |  View Paper