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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Carotenoids and Doxorubicin Hydrochloride

Research Papers that Mention the Interaction

Furthermore, mitochondrial dysfunction, cell growth arrest at G0/G1 phase and caspase cascades as well as up- and down-regulated expression levels of related proteins (p21, p27, Bax, p53, Bcl-2, and cyclin D1) revealed the synergistic effect of carotenoid and DOX treatment on ROS-mediated apoptosis.
The combination of carotenoids and doxorubicin (DOX) selectively alters oxidative stress-mediated apoptosis in breast cancer cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2018  |  View Paper
Furthermore, this carotenoid was neither mutagenic nor genotoxic to HL60 cells and reduced the DNA damage induced by doxorubicin.
Human & experimental toxicology  •  2016  |  View Paper
CARs prevented DOX induced variation in tissue architecture in heart and liver tissues.
Journal of cancer research and therapeutics  •  2014  |  View Paper