Possible Interaction: Carotene and Vitamin E

“Many other promising compounds have been identified, often as components of food, but results suggesting increased disease incidence with β carotene and vitamin E administration indicate that such treatments need rigorous evaluation before acceptance.”

“The antioxygenic aspect is represented … the sparing action of tocopherol on vitamin A and carotene which has been observed repeatedly, by the increased efficiency imparted to suboptimal doses of essential fatty acids (5), and the greater stability of the body fats when tocopherol is present in the diet (6).”

“ Vitamin E and β‐carotene levels were significantly higher (P < 0.05) in the combination group than in testosterone group.”

“While α‐tocopherol , t‐butyl‐1,4‐hydroxyanisole and allopurinol did not repress ulcer formation after BFMeT treatment, ascorbic acid, dimethyl sulfoxide, glutathione and β‐carotene significantly inhibited formation.”

“In the bone marrow cells of mice fed the carotene diet, alpha- and beta-carotene were detected, but … of the carotenes was less than one-hundredth of that of vitamin E. In addition, the feeding of carotene diet markedly reduced … concentration of vitamin E in bone marrow … and serum.”

“In general, chromatographic patterns obtained from the faeces and the relevant diet were similar, but there were notable differences in the concentrations of both tocopherol and carotene.”