Possible Interaction: Carotene and Vitamin C

“Conclusion This study suggests that total carotene and vitamin C intake from diet were inversely associated with deaths from all causes and cardiovascular disease in middle-aged or elderly people in China.”

“When the combined intake of vitamins C and E and carotene was considered, the protective effect of each nutrient was more marked or restricted to subjects with low intake of the other 2.”

“Partial correlation coefficients between carotene and ascorbic acid (0.69 in men; 0.74 in women), between carotene and alpha-tocopherol (0.44; 0.37), and between alpha-tocopherol and ascorbic acid (0.45; 0.41).”

“UNLABELLED Antioxidants are crucial components of fruit/vegetable rich diets preventing cardiovascular …., vitamins C + E, C + carotene, A + carotene); self-prescribed rectification of vitamins C …, carotene and conutrients also cancer; randomized exclusive supplementation of beta-carotene +/- vitamin A … lesions; high vitamin E supplements reveal potentials in secondary CVD prevention.”

“Inverse associations observed for carotene , vitamin E, and fiber from fruits and vegetables were diminished when adjusted for vitamin C intake.”

“2 A 12-year follow-up of this study found an inverse correlation of both carotene and vitamin C to cardiovascular risk.”

“While the protective effect of vitamin C and β‐carotene could conceivably be ascribed to other agents in the diet, the strong negative association between supplementation with vitamin C and risk of gastric cancer supports the hypothesis of a protective role of this anti‐oxidant.”

“Lens and kidney GSH‐Px activity, kidney GSH, vitamin E and β‐carotene concentrations and erythrocyte counts were increased by VCE treatment.”

“ Vitamin C caused slight enhancement to iron absorption, while carotene hindered it.”

“ Ascorbic acid pretreatment increased the retention of total carotenoids, ß‐carotene , TPC, and TFC (p < .05) by (6–11)%, (8–34)%, (7–58)%, and (6–30)%, respectively, for all the drying methods.”