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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Carnosine and Polypeptides





Research Papers that Mention the Interaction

We conclude that carnosine can react with protein CO groups (termed "carnosinylation") and thereby modulate their deleterious interaction with other polypeptides.
Free radical biology & medicine  •  2000  |  View Paper
We speculate that: (i) carnosine's apparent anti-ageing actions result, partly, from its ability to react with carbonyl groups on glycated/… proteins and other molecules; (ii) this reaction, termed 'carnosinylation,' inhibits cross-linking of glycoxidised proteins to normal macromolecules; and (iii) carnosinylation could affect the … of glycoxidised polypeptides.
Mechanisms of Ageing and Development  •  2001  |  View Paper
Carnosine ’s ability to reduce the formation of altered proteins (typically adducts of methylglyoxal) and enhance proteolysis of aberrant polypeptides is indicative of its influence on proteostasis.
Chemistry Central Journal  •  2013  |  View Paper