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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Carnosine and Doxorubicin Hydrochloride

Research Papers that Mention the Interaction

Carnosine treatment caused significant attenuation (p=0.05) of cardiac dysfunction induced by adriamycin (CAR+ADR), revealed by normalization of the ventricular function, ECG and biochemical variables.
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology  •  2011  |  View Paper
An increase in oxidative stress and inactivation of SOD, GSH-Px, CAT by a single dose of adriamycin were prevented when carnosine was given 2 weeks before and on the same day adriamycin treatment was administered.
Carnosine was given 2 weeks before and following adriamycin treatment.
Biological Trace Element Research  •  2010  |  View Paper
CAR normalized the values of MAP in rabbits receiving DOX and increased the values of CI and SI.
CAR seems to be cardioprotective during DOX administration.
The histopathological studies revealed smaller damage of cardiac muscle in rabbits which received DOX with CAR in comparison to animals receiving DOX alone.
Polish journal of pharmacology  •  2003  |  View Paper